Parkinson’s Disease - Looking Into This Mysterious Disease
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Parkinson’s disease, characterized by reduced dopamine production in brain cells is a kind of motor system disorder. Symptoms shown as a result of this health disorder vary from one person to another. Common symptoms shown as a result of this neurological disorder include slow movement, tremor and joint stiffness. People over the age of fifty are more prone to this health disorder. Apart from the above specified symptoms, people suffering from this health disorder may also show other symptoms like constipation, difficulty in swallowing, speaking and chewing.
What Causes Parkinson’s Disease?
Both genetic and environmental factors play equally important roles in causing this disease. Only 15 to 25 percent of the people suffering from this health disorder have reported genetic cause. If a person’s parent has PD, then he or she is more prone to this health disorder than general population. Gene mutation is another cause reported for the formation of this neurological disorder. As per research, this factor is found to be influenced in only a small number of people. Parkinson’s effect has reported at an early age in individuals with gene mutation in PINK1, DJ-1, LRRK2, parkin and glucocerebrosidase.
Exposure to environmental toxin is one of the main causes of Parkinson’s disease. Use of manganese, pesticides and contaminated well water are some of the common environmental causes reported for this neurological disease. Studies say that prolonged occupational exposure to certain toxins induce high chance of neurological disease in people. Chemicals reported for the increased risk of parkinsonisn among people include insecticides beta-HCH and permethrin, herbicide paraquat and fungicide maneb. MPTP, one of the renowned neurotoxins is another main cause of permanent and immediate parkinsonism. MPTP is one among the most rarely reported causes of parkinsonism among people. Most health experts suggest that the combination of genetic and environmental factors may cause the disease.
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